Tessident has displayed the ability to regulate bacteria to shift the oral microbiome from disease-causing to health-promoting within five days of use.*

Over 40 years of clinical and pre-clinical data is available on each active ingredient and all are Generally Regarded as Safe (GRAS) for intended use in foods.


The molecular technology in Tessident uses a multi-pronged approach called Selective Microbial Metabolism Regulation Technology (SMMRT) to regulate oral ecology for dental health:

  1. Stops sugar conversion into harmful by-products – A key ingredient in our formula is a sugar-decoy molecule that blocks sugar receptors and plaque-making enzymes, ultimately starving bacteria and leading to plaque breakdown.
  2. Encourages bacteria toward more health-promoting behaviors  – Our second molecule enables protein metabolism capabilities in bacteria, which produces health-promoting and protective by-products produced by bacteria. They provide you with essential nutrients, metabolize indigestible compounds, defend against colonization of opportunistic harmful bacteria, stimulate the immune system and contribute to overall health.
  3. Neutralizes saliva acidity – Sodium bicarbonate is used to bring saliva to a safe pH range for up to three hours. This allows for the calcium carbonate in the formula to re-mineralize teeth and strengthen enamel.

Supporting evidence: